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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIAA1432 All Species: 20.61
Human Site: Y431 Identified Species: 45.33
UniProt: Q4ADV7 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q4ADV7 NP_001129392.1 1423 159301 Y431 L Q G E D R L Y L N C G E A S
Chimpanzee Pan troglodytes XP_520477 1344 150402 I417 Y L E S N W P I R F S A I D K
Rhesus Macaque Macaca mulatta XP_001108907 1683 186726 Y692 L Q G E D R L Y L N C G E A S
Dog Lupus familis XP_541303 1427 158513 Y436 L Q G E D R L Y L N C G E A S
Cat Felis silvestris
Mouse Mus musculus Q69ZJ7 1422 158810 Y431 L Q G E D R L Y L N C G E A S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506289 1381 154436 L424 H P F P D G G L D S Q G L S T
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002665879 1098 121982 L204 S S T G C M Q L S H K L E L T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3C5 1429 159138 Y427 L Q G D D C L Y L N Q G N N L
Honey Bee Apis mellifera XP_395408 1410 158092 Y426 L Q G E D R L Y L N L G G G V
Nematode Worm Caenorhab. elegans Q09417 1470 163366 S433 A E A C A P H S V W D H I T V
Sea Urchin Strong. purpuratus XP_001183646 1434 158113 W422 I L A G N K Q W H C I Q I P Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.2 82.7 90.8 N.A. 92.8 N.A. N.A. 83.4 N.A. N.A. 55.1 N.A. 33.6 37.8 26.1 42.2
Protein Similarity: 100 94.3 83.3 94 N.A. 96.1 N.A. N.A. 88.7 N.A. N.A. 64.6 N.A. 52.4 57.8 43.4 61.2
P-Site Identity: 100 0 100 100 N.A. 100 N.A. N.A. 13.3 N.A. N.A. 6.6 N.A. 60 73.3 0 0
P-Site Similarity: 100 6.6 100 100 N.A. 100 N.A. N.A. 33.3 N.A. N.A. 20 N.A. 66.6 73.3 13.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 19 0 10 0 0 0 0 0 0 10 0 37 0 % A
% Cys: 0 0 0 10 10 10 0 0 0 10 37 0 0 0 0 % C
% Asp: 0 0 0 10 64 0 0 0 10 0 10 0 0 10 0 % D
% Glu: 0 10 10 46 0 0 0 0 0 0 0 0 46 0 0 % E
% Phe: 0 0 10 0 0 0 0 0 0 10 0 0 0 0 0 % F
% Gly: 0 0 55 19 0 10 10 0 0 0 0 64 10 10 0 % G
% His: 10 0 0 0 0 0 10 0 10 10 0 10 0 0 0 % H
% Ile: 10 0 0 0 0 0 0 10 0 0 10 0 28 0 0 % I
% Lys: 0 0 0 0 0 10 0 0 0 0 10 0 0 0 10 % K
% Leu: 55 19 0 0 0 0 55 19 55 0 10 10 10 10 10 % L
% Met: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 19 0 0 0 0 55 0 0 10 10 0 % N
% Pro: 0 10 0 10 0 10 10 0 0 0 0 0 0 10 0 % P
% Gln: 0 55 0 0 0 0 19 0 0 0 19 10 0 0 10 % Q
% Arg: 0 0 0 0 0 46 0 0 10 0 0 0 0 0 0 % R
% Ser: 10 10 0 10 0 0 0 10 10 10 10 0 0 10 37 % S
% Thr: 0 0 10 0 0 0 0 0 0 0 0 0 0 10 19 % T
% Val: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 19 % V
% Trp: 0 0 0 0 0 10 0 10 0 10 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 55 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _